Sync'Em doesn't work directly with the Palm but can help sync the Palm Pre indirectly. See Palm's site for more information.

The same applies for calendar events.

Note that this strategy will also work for Exchange (i.e., Outlook/OWA/Entourage) contacts because Sync'Em can also sync Exchange contacts/calendar events either with your Address Book/iCal or directly with your Google contacts/calendar events so you can get your Exchange contacts indirectly sync'd with your Palm Pre.

Yes, Sync'Em uses HTTPS/SSL to secure all communications with Google/Gmail accounts.